Yellow Fever Vaccination and Increased Relapse Rate in Travelers With Multiple Sclerosis

Yellow fever vaccination and increased relapse rate in travelers with multiple sclerosis.

OBJECTIVE To investigate the effect of yellow fever (YF) immunization on the subsequent multiple sclerosis (MS) relapse risk. DESIGN Self-controlled case series study. SETTING An MS outpatient clinic. PATIENTS Seven patients with clinical relapsing-remitting MS traveling to endemic YF areas who received the YF 17D-204 vaccine were studied. INTERVENTION The YF 17D-204 vaccine. MAIN OUT...

Increased Circulating miR-10a Levels Associated with Multiple Sclerosis

Background: Multiple sclerosis (MS) is an autoimmune disease that causes chronic inflammation of the central nervous system. MicroRNAs (miRNAs) are small non-coding RNAs 19–24 nucleotides long, which are differentially expressed in different tissues. The role of miRNAs in MS remains unclear. We assessed miR-10a transcript levels in MS patients during recurrence and two months after relapse. Ma...

Increased risk of multiple sclerosis relapse after in vitro fertilisation.

BACKGROUND Exogenous sexual steroids together with pregnancy have been shown to influence the risk of relapses in multiple sclerosis (MS). Treatments used during assisted reproductive techniques may consequently influence the short term evolution of MS by modifying the hormonal status of the patient. The objective of this study was to determine if there was an increased risk of developing exace...

Yellow Fever Vaccination: An Issue for Non-endemic Tropical Countries

Relapse management in multiple sclerosis.

Relapses, exacerbations, and attacks are synonymous for new or worsened neurologic symptoms that are the hallmark of relapsing-remitting multiple sclerosis. Management of relapses is not always straightforward. The clinician must distinguish between true relapses, symptom fluctuation, and pseudo-relapses. Risks and benefits of treating a relapse must be considered. Once the decision to treat is...